Cancer cells with a cell nucleus that is easily deformed are more sensitive to drugs that damage DNA. These are the findings of a new study by researchers at Linköping University in Sweden. The ...

Most genes known to control the cell cycle are mutated in cancer, some of them quite frequently. These include famous genes such as K-ras and p53. One notable exception is the cyclin-dependent kinase ...

Researchers at Kumamoto University have uncovered a previously unknown molecular mechanism by which human T-cell leukemia ...

Gastric cancer cells can activate KRAS-driven signals, enabling autonomous tumor growth by producing their own WNT proteins. New research reveals how gastric cancer cells exploit WNT signaling for ...

Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by ...

Long before a liver tumor appears, a high-fat diet can push liver cells into a risky survival mode. That is the central ...