About 100 cells divide every second in our body. A key protein in cell division is a protein kinase termed Plk1, because it activates other proteins involved in this process. Plk1 is also ...

Researchers at the Centre for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within ...

CAPTION: (Top) Condensins seem to act as a molecular crosslinkers to make loops. (Bottom, left) Condensins (red) locate around chromosome center. (Bottom, right) Nucleosomes around the periphery ...

Arteriovenous malformations, a hallmark of hereditary hemorrhagic telangiectasia, may be driven by endothelial cell-cycle acceleration via CDK6, suggesting potential for repurposing CDK6 inhibitors.

Just one enzyme manages the refilling of the cellular soda machine that replicates our genes. PLK-1 initiates a process in two protein groups, leading to creation of new CENP-A proteins. These CENP-A ...

Researchers found a genetic variant that appears to protect against the development of CHIP, a phenomenon that can lead to ...

Scientists have recently been learning more about the importance of small bits of circular genetic material known as extrachromosomal DNA (ecDNA). These little circles of DNA can hitch a ride with ...

New research sheds light on embryonic mitosis, thanks to a combination of novel imaging techniques, CRISPR/Cas9 genome editing technology, a modern protein-knockdown system, and medaka, or Japanese ...

A microscopic flaw in the brain’s cellular scaffolding can shape brain size for life.

Experiments on an ultra-rare genetic mutation that causes neurodegeneration in children have helped uncover a new mechanism ...