Baylor College of Medicine

Vector Development Lab

The VDL is currently restructuring and not providing services at this time. For all request of viral vectors, please visit the Gene Vector Core Website or send an email to [email protected]. Since ...
Nature

Production scale-up and validation of packaging cell clearance of clinical-grade retroviral vector stocks produced in Cell Factories

Regulatory requirements stipulate that the production of any agents intended for use in human clinical trials must be performed under current Good Manufacturing Practices (cGMP). 1 Retroviral vector ...
Science Daily

Researchers create new viral vector for improved gene therapy in sickle cell disease

Researchers have developed a new and improved viral vector -- a virus-based vehicle that delivers therapeutic genes -- for use in gene therapy for sickle cell disease. In advanced lab tests using ...
Nature

Gene Therapy Progress and Prospects: Development of improved lentiviral and retroviral vectors – design, biosafety, and production

Cis-elements within retroviral expression constructs increase vector titer and/or gene transfer efficiency. Several approaches for expressing multiple genes in a single vector are available. The ...