Almost 1,500 genes have been implicated in intellectual disabilities; yet for most people with such disabilities, genetic causes remain unknown. Perhaps this is in part because geneticists have been ...

Researchers are investigating the role of non-coding DNA, or junk DNA, in regulating astrocytes, brain cells involved in ...

When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...

Schematic representation summarising MASLD-associated long non-coding RNAs (lncRNAs) and their relevant targets in hepatocytes: human leukocyte antigen (HLA) complex group 18 (HCG18), nuclear enriched ...

Researchers at the Icahn School of Medicine at Mount Sinai and others have identified a neurodevelopmental disorder, caused by mutations in a single gene, that affects tens of thousands of people ...

Non-canonical proteins are unconventional protein products that are not part of the known protein-coding genome repertoire. They arise from unexpected translation of other genomic regions, from ...

Telomeres are repetitive sequences of DNA that can be found at the ends of chromosomes, where they form a kind of protective cap. Telomeres get shorter every time a cell divides, and they are thought ...

It has been claimed that because most of our DNA is active, it must be important, but now human-plant hybrid cells have been ...