Computational fluorescence microscopy (CFM) requires accurate point spread function (PSF) characterization for high-quality ...

descSPIM enables three-dimensional imaging of diverse tissues like neural cells and cancerous tumors. The widespread dissemination and adoption of descSPIM can accelerate biomedical discoveries. Three ...

Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

A new two-photon fluorescence microscope developed at UC Davis can capture high-speed images of neural activity at cellular resolution thanks to a new adaptive sampling scheme and line illumination.

Microscopes have long been scientists’ eyes into the unseen, revealing everything from bustling cells to viruses and nanoscale structures. However, even the most powerful optical microscopes have been ...

Introduction to SNOM: The Scanning Near-field Optical Microscope (SNOM) stands as a pivotal analytical tool in nanotechnology, enabling the visualization of nanostructures with resolution beyond the ...

What is the Diffraction Limit? The diffraction limit is a fundamental barrier in optical microscopy that sets the minimum size of features that can be resolved using conventional light microscopes. It ...