Mechanism of action of diuretics - UpToDate
Oct 1, 2024 · Natriuretic diuretics are among the most commonly used drugs. They act by diminishing sodium reabsorption at different sites in the nephron, thereby increasing urinary …
Diuretics and calcium balance - UpToDate
Jun 11, 2025 · Calcium reabsorption and urinary calcium excretion can be affected by the administration of diuretics. Calcium excretion is increased by loop diuretics and diminished by …
Loop diuretics: Dosing and major side effects - UpToDate
Jan 13, 2025 · The most commonly used loop diuretics are furosemide, bumetanide, and torsemide, which are sulfonamide derivatives. Ethacrynic acid is rarely used but is an …
Time course of loop and thiazide diuretic-induced electrolyte ...
Apr 28, 2025 · Therapy with a loop- or thiazide-type diuretic may be associated with a variety of fluid and electrolyte complications, including volume depletion, azotemia, hypokalemia, …
Effect of diuretics on magnesium handling by the kidney
Nov 11, 2024 · Diuretics are widely used in the treatment of hypertension, heart failure, cirrhosis, and kidney diseases. Three types of diuretics are known to influence magnesium homeostasis:
Thiazides versus loop diuretics in the treatment of hypertension
Oct 4, 2024 · Diuretics, particularly thiazide-type and thiazide-like diuretics, are commonly used in the treatment of hypertension. Diuretics lower the blood pressure, at least initially, by inducing …
Overview of the management of chronic kidney disease in adults
Mar 26, 2025 · This process appears to be responsible for the development of kidney failure among those in whom the original illness is either inactive or cured [1]. Estimates of single …
Possible prevention and therapy of ischemic acute tubular necrosis
Oct 13, 2025 · INTRODUCTION Acute kidney injury (AKI) due to ischemic acute tubular necrosis (ATN) typically lasts 7 to 21 days [1], with most patients returning to or near their previous …
Treatment of resistant hypertension - UpToDate
Oct 22, 2025 · INTRODUCTION Resistant hypertension is defined as a blood pressure that remains above goal despite concurrent use of three antihypertensive agents of different …
Medline ® Abstract for Reference 7 of 'Effect of diuretics
These results are consistent with a luminal effect of furosemide in the loop of Henle that inhibits calcium and magnesium transport to a greater degree than sodium chloride. Intraluminal …